
Prednisolone, what is it? What are the effects?
Luppies or anyone with a chronic condition will likely have a love-hate relationship with Prednisolone.
I thought it would be a good idea to do a little research into this drug that I have been taking on and off for over a decade and write this blog post in the hopes that it could help anyone that has been newly diagnosed or even the friends and family of a person with a chronic condition for them to provide support.

What is Prednisolone?
Prednisolone is a synthetic natural substance (corticosteroid hormone) produced by the adrenal glands and used to treat arthritis, blood problems, immune system diseases, skin and eye diseases, respiratory diseases, cancer, and allergies. It reduces the immune system’s response to various conditions to relieve symptoms such as pain, swelling, and allergic reactions.
How to use oral Prednisolone?
How to use oral Prednisolone?
• Take this medication by mouth, food, or milk precisely as your doctor directs to avoid indigestion. Dosing with a special measuring device/spoon.
• Do not use homemade spoons because you will not get the correct dosage.
• Liquid prednisone has many brands, advantages, and forms. Please read the dosage instructions for each product carefully, as the dosage of Prednisolone varies from product to product. See also the precautions and storage section. Follow the dosage plan carefully.
• The dose and duration of treatment will depend on your health and response to treatment.
Side Effects
Side Effects
You may experience
• Nausea
• Heartburn
• Headache
• Dizziness
• Menstrual cycle changes
• Sleep disturbance
• Increased sweating
• Acne
Please tell your doctor or pharmacist immediately if these effects persist or worsen. Remember, your doctor prescribed this medicine because they found it beneficial.
Infections: Many people who take this drug do not experience severe side effects. Because this drug weakens the immune system, it reduces your ability to fight infections. This increases your chances of getting severe (rarely fatal) infections or developing a specific type of infection. Please tell your doctor immediately if you have any signs of infection (such as cough, sore throat, fever, or chills).
Yeast Infections: Long-term or repeated use of this drug can cause thrush or yeast infections. If you notice white spots in your mouth or changes in vaginal discharge, consult a doctor.
Blood Sugar Level: In rare cases, this drug can increase blood sugar levels, which can cause or worsen diabetes. If you have symptoms of high blood sugar, please tell your doctor immediately. For example, your doctor may need to adjust your diabetes medication, exercise plan, or diet.
Serious Side Effects
If you experience any of these unlikely but severe side effects, please tell your doctor immediately:
• Abnormal tiredness
• Swollen ankles/foot
• Abnormal weight gain
• Blurred vision
• Easy bruising/bleeding
• Facial swelling
• Abnormal hair growth
• Mental Mood swings/changes (depression, mood swings, agitation)
• Muscle weakness/pain
• Thinning of the skin
• Slow wound healing
• Bone pain
• Chest Pain
• Cramps
• Gastric/intestinal bleeding symptoms (such as stomach/stomach pain, black stool/tar, ground-like Vomiting)
Severe Allergic Reactions
Very severe allergic reactions to this drug are rare. However, if you experience symptoms of a severe allergic reaction such as skin rash, seek medical help immediately. Itching/swelling (especially face/tongue/throat), severe dizziness, shortness of breath.
Does Prednisolone interact with other drugs you are taking?
Drug interactions can change how drugs work or increase the risk of severe side effects. Keep a list of all your products and tell your doctor and pharmacist. Do not start, stop or change the dosage of any medicine without your doctor’s approval.
Some products that may interact with this drug are aldesleukin and other drugs that weaken the immune system, such as azathioprine, cyclosporine, cancer chemotherapy, and mifepristone, which may cause bleeding/bruising. Medicines (including antiplatelet drugs such as clopidogrel, “blood thinners” such as dabigatran/warfarin, and non-steroidal anti-inflammatory drugs such as aspirin/celecoxib/ibuprofen) interact with it.
Other products, such as estrogen, azole antifungal drugs, rifamycin, and St. John’s wort, can affect the removal of Prednisolone from the body will affect the effects of Prednisolone. For more information, please consult your doctor or pharmacist.
This product will affect specific laboratory tests (such as skin tests). Ensure that the laboratory staff and your doctors know you are taking this medication.
Have you ever had to take Prednisolone?
How did it affect you?
Please comment below
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